The German Heart Center of the Free State of Bavaria associated to the Technical University of Munich is a clinic with international reputation and a state of the art technical and medical equipment.

 

The Sager Laboratory of cardiovascular inflammation at the Department of Cardiovascular Diseases is seeking a


PhD student (m/f)
(Promotionsstelle)


Position:

The "European Research Council starting grant" research group of Dr. Hendrik Sager is looking to recruit a highly-motivated PhD student to join a dynamic international research team at the German Heart Center Munich, department of cardiology. Our research focusses on the role of the immune system in cardiovascular disease. Specifically, we are interested in the origin, function and fate of innate immune cells (monocytes, macrophages, neutrophils) in atherosclerosis and wound healing after myocardial infarction. Based on new mechanistic understanding, we seek to develop novel therapeutic concepts. We are part of the German Heart Center Munich and aim translate our findings to better understand and improve human health. We are funded by the “European Research Council (ERC Starting Grant 2017 awarded to H. Sager)”, "Deutsche Forschungsgemeinschaft", "Deutsches Zentrum für Herz-Kreislauf-Forschung", "Else-Kröner-Fresenius-Stiftung" and "Deutsche Herzstiftung".


Requirements:
The successful applicant should have an excellent command of flow cytometry techniques, in addition to standard
molecular biology.


Your application should include:

- Cover letter describing your research interest and why you are suitable for the position (maximum 1 page)
- CV including a list of relevant publications
- Copy of the official academic transcript of your degree or a letter stating when your degree will be obtained
- Names, e-mail addresses, and telephone numbers for academic references/recommendation letters


,
Recent publications:
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Sager HB, Hulsmans M, Lavine KJ, Beltrami Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman
JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M.
Circ Res. 2016 Sep 16;119(7):853-64. doi: 10.1161/CIRCRESAHA.116.309001. (IF=11.6)


RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after
myocardial infarction.
Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K,
Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK,
Anderson DG, Nahrendorf M.
Sci Transl Med. 2016 Jun 8;8(342):342ra80. doi: 10.1126/scitranslmed.aaf1435. (IF=16.3)


Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R,
Libby P, Swirski FK, Nahrendorf M.
Circulation. 2015 Nov 17;132(20):1880-90. doi: 10.1161/CIRCULATIONAHA.115.016160. (IF=17)


Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.
Dutta P*, Sager HB* (contributed equally), Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M,
Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F,
Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M.
Cell Stem Cell. 2015 May 7;16(5):477-87. doi: 10.1016/j.stem.2015.04.008. (IF=22.4)


Chronic variable stress activates hematopoietic stem cells.
Heidt T*, Sager HB* (contributed equally), Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C,
Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M.
Nat Med. 2014 Jul;20(7):754-8. doi: 10.1038/nm.3589. (IF=27.4)


Our offer:
The position covers a three-year period with possibility of extension, starting as soon as possible. The salary is based on
the TV-L (70% German TV-L E13).
The German Heart Center Munich promotes professional equality between women and men and provides the same
employment opportunity for severely disabled people in case of equal qualifications.


Contacts:
-  Hendrik Sager, MD, Principal Investigator, telephone +49 89 1218 2935
-  Thomas Schmid, Head of Recruiting/HR, telephone +49 89 1218 1734


More informations you find also at our homepage:

http://www.dhm.mhn.de/de/kliniken_und_institute/klinik_fuer_herzund_ kreislauf/wissenschaftliche_arbeitsgrupp/kardiovaskulaere_inflammation.cfm


Please send us your application until October 31th, 2017 by E-Mail to: career@dhm.mhn.de

Interview expenses will not be reimbursed.

Kontakt für Bewerbung

Herr Thomas Schmid
Personalgewinnung
Stv. Personalleiter

Arbeitsort

Lazarettstr. 36, 80636 München

Mehr zum Job

Anzeigenart Praktikum, Werkstudent, Abschlussarbeiten
Arbeitszeit Vollzeit
Vertragsart Befristete Anstellung
Berufliche Praxis keine Angabe
Aus- und Weiterbildung Abschluss Hochschule / Berufsakademie / Duales Studium
Berufskategorie Gesundheit, Medizin, Pflege, Sport / Arzt, Mediziner
Arbeitsort
Lazarettstr. 36, 80636 München