Biotransformation Scientist - Lab Head (f/m/d) in Grafing

For our DMPK expert Center at Grafing near Munich, we are looking for a highly motivated Biotransformation Scientist – Lab Head (f/m/d) with experience in metabolite profiling and structure elucidation to join our Biotransformation team in Grafing near Munich. In the role as head of laboratory, you will investigate and work on the biotransformation of small molecules and peptides being part of discovery and development studies we perform for our clients. If you are someone with excellent scientific and organizational skills, a good understanding of UPLC-HR-MS, and if you are fully committed to team work, this is a great opportunity for you.


  • Leading a small team of engineers/laboratory technicians and maintaining the laboratory environment and instruments 
  • Planning, executing, and reporting client-based metabolism experiments in the role as study director or responsible scientist
  • Organizing and coordinating work and work packages within the laboratory in order to ensure optimal employment of resources as well as smooth and timely interaction with other departments and clients
  • Ensuring adequate training of staff in order to further develop capabilities and strengths and ameliorate where gaps are identified
  • Keeping abreast with current advances in MS including automation and applying new methodologies for increasing sensitivity, throughput, and for accelerating research to improve the quality of scientific data in drug development
  • Evaluation and implementation of new technologies, techniques, and skills in accordance with the department strategy and following literature in the area of drug metabolism, metabolite identification, UPLC-MS, and radio detection
  • Maintaining awareness of the latest developments in the area of drug metabolism and its relation to drug safety
  • Compliance with German law, GLP, and GCP guidelines as well as with other applicable regulations (e.g., radio protection) pertaining to the R&D process, study conduct, and registration of drugs.
  • Enforcing adherence to safety measures in laboratories (accountable as per delegation)



  • PhD in biochemistry, chemistry, pharmacy, or a related field, with postdoctoral training or previous relevant experience in the pharmaceutical, biotech industry, or CRO (at least 5 years)
  • Hands-on experiences in operating and maintaining UPLC and high resolution mass spectrometric equipment for the purpose of metabolite identification and characterization of small molecules, peptides, oligonucleotides, or proteins
  • In-depth experience and knowledge of drug metabolism as well as in the interpretation of mass spectral data for metabolite structure elucidation
  • Hands-on experiences in working with radioactivity
  • Experiences in leading small to mid-size teams


Experiences to work in a highly regulated (GLP) environment

You are autonomous, organized, rigorous, versatile and easily adaptable to a fastpaced environment with good communication and written skills. You have a sense of analysis, a developed spirit of synthesis. Your teamwork skills are recognized and you take initiatives.

Fluent in English and German

Mehr zum Job

Anzeigenart Stellenangebot
Arbeitszeit Vollzeit
Vertragsart Festanstellung
Berufliche Praxis mit Berufserfahrung
Aus- und Weiterbildung Abschluss Hochschule / Berufsakademie / Duales Studium
Berufskategorie Produktion, Forschung und Entwicklung / Forschung und Entwicklung
Arbeitsort Am Feld 32, 85567 Grafing


Nuvisan GmbH

Kontakt für Bewerbung

Frau Hannelore Grafe

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